The relationship between Bofoi and Drive Knight is currently unknown. However, Drive Knight appears to know Bofoi enough to not trust him. He warns Genos not to trust him either, and even tries to convince Sekingar that Metal Knight is a traitor to the Hero Association, showing that Drive Knight has some sort of agenda against Bofoi.
How much Drive Knight knows about Genos is unknown. However, he was willing to warn him to not trust Metal Knight, stating that he is Genos' enemy. When Genos saved him and Sekingar from G5, Drive Knight seemed indifferent to seeing him again.