Psykos/Synopsis

History
Psykos was a colleague and good friend of Fubuki. She was the vice president of the "Society for Supernatural Research" during high school. When she was 17 years old, Fubuki sealed away Psykos's psychic power due to her proposal of wiping out humanity to the Supernatural Society. At some point in the past, Psykos saw a vision of the future about humanity that drove her mad and she founded the Monster Association. She was responsible for making Orochi into a powerful monster through a special nurturing process, which stimulates growth in humans to make them into monsters. Countless horrible experiments including cannibalism, breeding, blood, and cell transfusions, and torture were conducted during this process to create a strong monster.

At some point after this, she and Orochi abducted Gouketsu and offered him more power in exchange for his cooperation which he accepted.

Super Fight Arc
Psykos is speaking with Monster King Orochi about the monster raid's situation through her "meat puppet," Gyoro Gyoro.

After Tatsumaki killed the Hundred-Eyes Octopus, Psykos finds the situation troublesome, but Orochi sees it as not a concern because they can make as many Mysterious Beings as they please.

Through his robot, Bofoi questions Orochi and Psykos about their goals and while they tell him destruction is a natural part of a monster's instincts, it is not their end goal.

Psykos denies Phoenix Man's request to reinforce the cornered monsters and orders Gouketsu to return from the C-City Super Stadium.

Monster Association Arc
Destrochloridium takes over the body of a Hero Association staff member and infiltrates the Hero Association with one of Psycho's drones to deliver a message to the Hero Association. She briefly pretends that the Monster Association's goal is merely to live in peace and be free from the threat of elimination. However, when a Hero Association staff member promises that they won't touch the Monster Association, Destrochloridium kills him, and Psykos reveals that they were just joking. The real message was that the Monster Association was declaring war and that they would give the HA 3 days to prepare. The hostage was only taken to ensure that the Hero Association couldn't ignore the challenge.

She gives a massive speech to the members of the Monster Association and witnesses Orochi eat Awakened Cockroach, as well as persuading Orochi to spare Do-S for her useful ability. Through her drones, she sees Gouketsu's headless corpse.

Psykos leaves a message to Garou telling him to rest within his cell. Later, Psykos was seen deciding on the fate of Narinki's Private Squad that attacked them. Psykos questioned G5 on how he found out about the Monster Association and answered the Machine God's question on attacking other monsters. Afterward, Psykos offered a deal to Garou to join the Monster Association as an executive member to help boost their forces after the loss of Elder Centipede and Gouketsu. When Garou left to kill a hero, Psykos ordered Royal Ripper and Bug God to tail Garou and watch his movements. Phoenix Man later questions Psykos on the purpose of sending combat types to observe Garou as both Royal Ripper and Bug God can decide to kill Garou on a whim. Psykos reveals that it is a test and to facilitate Garou's growth, stating that he needs to be ravaged both physically and mentally. Psykos, in particular, is excited to see what changes Garou will undergo as a result of experiencing monsters. Psykos further reveals to Phoenix Man that Orochi was once a human that, after countless failures and sacrifices, became the ultimate being. Psykos created Orochi and that only it knows the secret trick of doing so. Psykos mentions that with the right nourishment, Garou has the potential of becoming a second Orochi, but that if he dies then he was never good enough.

During Royal Ripper and Bug God's report about Garou, she sees through Ripper's lies and asks him to tell the truth in which Bug God tells what really happened during their fight with Garou. Afterward, Royal Ripper begins to question the fact that Garou was quite a formidable foe, which is why Psykos intentionally sent them after the Hero Hunter since he knew both of them would turn on the Human Monster and strong enough to potentially kill him. Psykos then asks whether he is dead in which both Royal Ripper and Bug God respond that he probably is, despite not checking on him carefully.

As he takes note of Tareo, he wonders who he is in which Royal Ripper states that he is his toy to play with or else he would have to cut someone else to quell out his blood lust. Consequently, Psykos angrily scolds him not to playing around since he had found the scouting robot used by Child Emperor to scout the Monster Association HQ and firmly stating that the S-class heroes are not to be taken lightly as she assumed that one of them executed Elder Centipede and Gouketsu as well as the fact she doesn't know the secret weapon, the Hero Association is hiding.

Later, when Garou takes a secret tunnel into the Monster Association base, Psykos immediately detects that there is an intruder. She only recognizes that the intruder is sending a biological signal, and is either a human or a monster. She sends monsters to Garou's location with orders to kill the intruder if it is a hero and welcome it if it is a monster. Garou's rampage attracts Overgrown Rover, who assaults him and sends him crashing into Psykos' private room. Psykos is pleasantly surprised to see Garou alive, complimenting him for living up to her expectations and for growing so much stronger. She lifts the rubble off of Garou, but then forcefully restrains him. She asks Garou to have a quick talk.

Psykos tells Garou the secret of breaking the limiter as someone who must repeatedly experience death and overcome it. He goes over his experiences and experiments to arrive at that answer and shows Orochi as his first success. He attempts to convince Garou to let him raise him into the most powerful monster, but he refuses. When Garou begins to adapt to the psychic restraint, he lets Orochi battle him. At some point, Psykos tells Rhino Wrestler that he has improved and became a Demon-level threat.

Psykos watches as the heroes strike team to attack the wave of monsters in the ghost town of Z-City. After the battle, he calls upon, Black Sperm, Nyan, Homeless Emperor, Gums, Orochi and Fuhrer Ugly for a talk. During the Monster Association invasion, Gyoro Gyoro meets Tatsumaki at the Association main hub and both start to fight. Gyoro Gyoro goes for the offensive and releases an immense barrage of energy and rubble to crush Tatsumaki inside a condensed ball of concrete. However, his attack is ineffective as it is revealed that Tatsumaki is unfazed and she proceeds to blow Gyoro Gyoro's arm off. Impressed by Tatsumaki's esper powers, Gyoro Gyoro transforms into his true form, becoming bigger and gaining many more eyes on his body. He continues to Tatsumaki by increasing the gravity around her 300 times, only for the hero to be unharmed. Tatsumaki retaliates against Gyoro Gyoro by tearing him apart effortlessly. Gyoro Gyoro admits that Tatsumaki's powers are much greater than he originally perceived but still complains that she finished him off so brutally. Tatsumaki asks him why he is complaining since meat puppets are supposed to not feel pain and tells him that she will force his body out of the puppet. Shocked by this, Gyoro Gyoro calls for Orochi as an act of desperation and is shocked when the Monster King doesn't show up, wondering what kind of opponent he is facing so that he could even ignore Gyoro Gyoro's command.

Gyoro Gyoro sends a spy drone to discover who attacked Orochi. After finding the mask of Orochi and believing him to have been defeated, the drone tries searching around and detects King, and the latter runs away from the drone upon seeing it. As the spy drone pursues King, Saitama suddenly appears behind the drone and destroys it with a clap. Gyoro Gyoro, not fully understanding what just happened, believes that King managed to sneak behind the spy drone and destroy it so quickly that it did not even realize. Tatsumaki levitates Gyoro Gyoro's devastated body and the monster attempts to attack the hero with multiple energy beams but fails to do any damage. She proceeds to rip a body out from inside Gyoro Gyoro, but discovers that it is just a meat puppet. She then senses the presence of the true puppeteer deep underground, Psykos, and turns her attention towards the latter to finish the job. Elsewhere, Fubuki senses her sister's psychic energy and is shocked at the level of power she is using.

Tatsumaki realizes that the body she pulled out of Gyoro Gyoro was not its real form but in fact just a "regular lump of meat" and that in reality its real form, Psykos, had been controlling the meat puppet from a safe location 1500 meters underground. After Gyoro Gyoro having been destroyed by Tatsumaki, Psykos decides to bide her time by remaining hidden underground while preparing a new meat puppet and waiting for the Executives to finish off their targeted heroes and then corner and surround Tatsumaki to defeat her.

But then, to Psykos's surprise and dismay, Tatsumaki realizes where she is hiding in a matter of seconds through her powerful long-range psychic sense and then proceeds to be overwhelmed by her psychokinesis. In a desperate attempt for help, Psykos decides to try to send Overgrown Rover to attack Tatsumaki through her maximum output telepathy but the monster is too busy battling Bang, Bomb and Fubuki. After getting no response Psykos sees Saitama riding in a minecart towards the Inner Sanctum of the Monster Association Headquarters through one of her many eyes placed throughout the base. She, however, does not see Flashy Flash riding with him as he is obscured by Saitama's hand and cape. That combined with the fact that Tatsumaki has discovered her location and that none of the executives are there to assist her, Psykos decides that her only option is to engage in battle with Tatsumaki herself, drinking a potion to enhance her psychic abilities beforehand, and flies up to confront the esper hero.

Psykos is easily defeated by Tatsumaki, who interrogates her for intelligence. Psykos informs her of the outsiders in the hideout: Tareo, Narinki's Private Squad, and Garou. Immediately after, Orochi arrives, and his appearance distracts Tatsumaki long enough for Psykos to escape her hold. Upon seeing that Orochi is still alive, Psykos tries to merge with him to gain enough power to beat Tatsumaki. Orochi attempts to devour her, but Psykos resists, stating that she is the master and Orochi is nothing more than a power-amplifying vessel. Suddenly, she has a vision of a spherical, multi-layered surface in space. She wonders if it's a brain, a diagram of the universe, or Jupiter, before deciding that it's something like God. The surface then peers into Psykos, who simultaneously feels fear, the power coursing through her, and a realization of her destiny. Psykos successfully overpowers Orochi's will with her own, taking over their merged form and joining Orochi's fight against Tatsumaki, also continuing to send out Orochi's flesh to devour other life forms, although Orochi still maintains a level of control and constantly threatens to overpower Psykos's will as shown by her face deteriorating into a mass of Orochi's flesh. While Psykos initially has the upper hand, she quickly loses it when a chunk of Orochi's flesh is vaporized by Saitama's punch. When Tatsumaki lifts the Monster Association base above the ground, Psykos and Orochi emerge from the tallest building with an explosion. Psykos deems Tatsumaki's display of power gaudy, asking if she's showing off. When Tatsumaki attempts to attack, Psykos remarks that she's already superior to Tatsumaki power-wise and retaliates with a devastating energy beam that cuts through the Earth's surface as it passes through. Psykos laughs and deems her power splendid, also wondering if her vision was real. She brags that she was bestowed a power superior to Tatsumaki's and is now a perfect life form, the final representative of fate. She states that Tatsumaki and Fubuki will be defeated due to their lack of seriousness about the future of psychic powers. When called an idiot by Tatsumaki as well as being called out for being forced to rely on Orochi for everything, Psykos flies into a rage, sending several of Orochi's dragons after Tatsumaki and releasing another series of energy blasts.

Tatsumaki dodges the energy blasts and then lifts several large rocks out of the ocean and hurls them at the fusion, attempting to trap them. The fusion breaks out, and a whirlwind of rocks and energy fills the sky as the two unleash their power. Psykos, despite her visibility being impaired by the rocks, senses Tatsumaki's psychic signature and hits her with energy beams. However, she then sees that the signature she caught on to was actually a dummy, and realizes all too late that Tatsumaki had entered her body through one of the tendrils in her root system. Tatsumaki comments on how Psykos's body is hollow from the inside and quickly destroys it by twisting it. Psykos manages to survive and begins reforming her body as the fusion impales both of Tatsumaki's hands on their blades and strikes her with a powerful jolt of psychic power. Psykos charges up another powerful energy beam, but Tatsumaki is saved by Genos, who launches an energy beam of his own to intercept. The fusion between Psykos and Orochi and Genos exchange energy beams. Genos holds them off long enough for Tatsumaki to rescue the infiltration squad, causing her to return to the fight and begin twisting the entire city in order to destroy the roots of the creature. She then begins twisting the fusion itself, causing both Orochi and Psykos to roar in agony as their bodies begin to forcibly separate. The fusion of Psykos and Orochi transforms into a jet and tries to consume the blood from the humans in the city. Tatsumaki senses that their presence is divided into seven due to Psykos using the same technique that Tatsumaki used before, but she manages to create a giant psychic barrier surrounding them so that the monster won't be able to escape. Psykos tries to pierce Tatsumaki's heart using a laser attack, as she believes the esper hero needs to take all of her concentration to maintain the barrier so large, thus this is a chance to finish her off, but she ends up hitting a dummy created by the hero. Tatsumaki now knows her location thanks to the dummy. Drive Knight then appears and joins their battle.

Drive Knight and the fusion monster continue their clash inside Tatsumaki's psychic barrier.

Psychic Sisters Arc
Psykos is later seen in A-City's secret prison where the other imprisoned monsters are, being interrogated by Fubuki to answer why Psykos built Monster Association and what future does she see, with Saitama asking her why she and her Association attacked his former hometown, but Psykos, due to her previous defeat by Fubuki, is mentally broken and unable to give a clear answer. However, the real reason why Fubuki has come after Psykos was because Fubuki's older sister, Tatsumaki is now coming after Psykos and wishes to kill her. Fortunately, Saitama protects Psykos when Tatsumaki and Fubuki are causing destruction throughout the Hero Association faculty. Psykos quickly becomes unconscious during the ruckus, along with the police Fubuki knocks out due to an emergency caused by Tatsumaki's sudden arrival. Fubuki keeps her sister busy at this time. As Tatsumaki stops her own madness, an unconscious Psykos is taken by Fubuki safely.

After being unveiled as a human, Psykos weakens Tatsumaki as she lowers her defense in preparation for fighting the Dragon-level monsters. Psykos is then challenged by Fubuki and is defeated by the B-Class hero.

Psychic Sisters Arc
Psykos is later seen in A-City's secret prison where the other imprisoned monsters are, being interrogated by Fubuki to answer why Psykos built Monster Association and what future does she see, with Saitama asking her why she and her Association attacked his former hometown, but Psykos, due to her previous defeat by Fubuki, is mentally broken and unable to give a clear answer. However, the real reason why Fubuki has come after Psykos was because Fubuki's older sister, Tatsumaki is now coming after Psykos and wishes to kill her. Fortunately, Saitama protects Psykos when Tatsumaki and Fubuki are causing destruction throughout the Hero Association faculty. Psykos quickly becomes unconscious during the ruckus, along with the police Fubuki knocks out due to an emergency caused by Tatsumaki's sudden arrival. Fubuki keeps her sister busy at this time. As Tatsumaki stops her own madness, an unconscious Psykos is taken by Fubuki safely.

Neo Heroes Uprising Arc
Psykos is taken into Fubuki's mind room, where Fubuki has spent several hours every day telepathically connecting with Psykos. She is seen in a mental mindscape with grasslands and a cloudy sky, standing in front of Fubuki. Psykos explains that she failed, and that there is no forgiveness for her failure. When Fubuki asks Psykos who she is referring to, she replies that she doesn't know, greatly unsettling Fubuki.