House of Evolution

The House of Evolution is an organization founded by the genius doctor, Dr. Genus, to pursue the goal of human perfection through artificial evolution. It serves as the first antagonist faced by Saitama alongside his new disciple, Genos. All of the staff of the organization are actually clones of the original doctor. Based on the names and designs of their warriors, the House of Evolution's primary focus seems to be improving humanity through gene splicing with the DNA of other species of animals.

The House of Evolution is headquartered in a thin, skyscraper-like building with eight stories in a forest approximately four hours walk from Saitama's apartment, although it also connects to expansive underground facilities. The above-ground section of the base was obliterated by Genos upon his and Saitama's arrival. The base's underground facilities include an enormous chamber for combat testing of new specimens, and the containment chamber used to imprison Asura Rhino.

After the partial destruction of its headquarters and the death or defeat of its strongest warriors at the hands of Saitama and Genos, the organization appears to be effectively defunct. Although the doctor and some of his clones survive, he resolves to give up his experiments after watching his most powerful artificially evolved creature, Asura Rhino, killed easily in his strongest form by the inexplicably powerful Saitama.